JEJUNAL VILLUS ABSORPTION AND PARACELLULAR TIGHT JUNCTION PERMEABILITY ARE MAJOR ROUTES FOR EARLY INTESTINAL UPTAKE OF FOOD-GRADE TIO2 PARTICLES: AN IN VIVO AND EX VIVO STUDY IN MICE

Abstract Background Food-grade TiO2 (E171 in the EU) is widely used as a coloring agent in foodstuffs, including sweets.Chronic dietary exposure raises concerns for human health due to proinflammatory properties and the ability to induce and promote preneoplastic lesions in the rodent gut.Characterization of intestinal TiO2 uptake is essential for

In this study, housing demand in Turkey was examined with Bounds Testing Approaches for the period of 1964-2014.The total square meters of houses sold was taken as housing demand.The explanatory variables of the study are the real price Advanced Wound Care - Cleansers of one square meter of housing, real income level, and urban population.Firstly,

This work attempts to approach the changes in the models of social reproduction Flea of the noble family from the 15th to the 19th century in Spain, as well as the emergence of individualism.In this way, starting with a family analysis of two complete noble lineages, the de la Cueva and Fernández de Córdoba, which cover 54 houses or genealogical

The strategies of crossing B.napus with parental species play important role in broadening and improving the genetic basis of B.napus by the introgression of genetic resources from parental species.With these strategies, it is easy to select new types of B.napus, but difficult to select new types of B.rapa or B.oleracea by self-pollination.This cha

IntroductionCancer-associated fibroblasts (CAFs) are a diverse group of cells that significantly contribute to reshaping the tumor microenvironment (TME), and no research has systematically explored the molecular landscapes of senescence related CAFs (senes CAF) in NB.MethodsWe utilized pan-cancer single cell and spatial transcriptomics analysis to